54. Dual stimuli-responsive polyamines derived from modified N-vinylpyrrolidones through CuAAC click chemistry
A. del Prado, R. Navarro, P. A. Levkin, A. Gallardo, C. Elvira and H. Reinecke
J. Polym. Sci. A, 2016, 54, 1098–1108
The synthesis via copper(I)-catalyzed azide alkyne cycloaddition (CuAAC) of three new monomer derivatives of N-vinyl-2-pyrrolidone (VP) carrying cyclic pyrrolidine, piperidine, and piperazine groups and the corresponding copolymers with unmodified VP is shown. The systems bearing pyrrolidine and piperidine displayed both thermo- and pH-response, which has not been reported previously for a polymer with polyvinylpyrrolidone (PVP) backbone. A broad modulation of the LCST with the copolymer composition and pH was observed in a temperature range 0–100 °C. The polymers carrying piperazine exhibited broad buffering regions and no thermosensitivity.
